When transfering a patient from isosorbide dinitrate standard release to isosorbide mononitrate standard release, is it a same dosage switch?

Responses:

The SPC for Ismo states:

“For those previously treated with isosorbide dinitrate in conventional form the dosage of Ismo should be the same initially. Ismo is effectively twice as potent as sustained release forms of isosorbide dinitrate and patients transferred from such treatment should receive Ismo at half the previous dosage.”

Source: http://emc.medicines.org.uk/emc/assets/c/html/displaydoc.asp?documentid=16325

Conflict of Interests - none